If you are powering the Quadrino using an ESC it is likely that you have a blown protection diode. This diode is labeled D2 and is located just above the middle slot in the board. This diode protects the ESCs from USB power coming from the computer, and thus preventing the chance that you might get bit by props when plugged into USB, (as has happened to me way back.)

The cause of the diode blowing is the board's (+) supply was at least momentarily connected to GND(-). First, ensure your wiring is correct and use a multi-meter to ensure power lines are not shorted. This is called a HI-POT test.

It can simply also have been caused by a stray screw or exposed wire shorting the power pins, so your wiring maybe fine after all. The advent of the EZ-connect has largely rid the case of blown diodes since power pins are no longer directly exposed.

Open a ticket with us and we will solve your problem. We will either send you some spare diodes, or you can send your unit in to us and we will replace the diode free of charge.